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Rome were equally susceptible to this mosquito-borne killer; yet this surprising reality was actually the impetus behind the search for a cure and the eventual discovery of quinine.
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Acids or enzymes are used to break down cornstarch into a syrup rich in maltose (35 percent or more), a disaccharide.
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Only qui-nidine, an isomer of quinine, has been reported more often as a cause of isolated thrombocytopenia (), but reports of quinidine-induced thrombocytopenia are now uncommon, as it is used much less often for treatment of cardiac arrhythmias.
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However the destruction of (cinchona) trees to obtain quinine made them rare and so a way of making it synthetically was sought.
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