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Patients who are treated early may recover quickly on outpatient medication, while those who experience a more severe course may require intravenous antibiotics, prolonged hospitalization or intensive care.

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Approximately 50% of hepatotoxicity has been observed during the first month of therapy.

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Doctors can indirectly assess pancreatic function with a 72-hour stool collection, in combination with a three-day dietary record, to determine how much fat a child is absorbing from the food he or she is eating.

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Rifampin is concentrated in polymorphonuclear granulocytes and macrophages, facilitating clearance of bacteria from abscesses.

Finally, before COXIB therapy is initiated, the patients cardiovascular CV risk must be determined.

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Avoid the use of drugs that also increase QT interval and in patients with risk factors for prolonged QT interval.

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It is also being studied in the prevention of breast cancer in certain premenopausal women and in the prevention and treatment of other conditions.

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ULN; median onset after 38 days, 87% with symptoms, bilirubin not mentioned; pyrizinamide most frequently implicated; factors associated with injury were age, female sex, autoimmune disease and HIV infection).

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Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

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MDR) TB (resistant to both isoniazid and rifampin) or extensively drug-resistant (XDR) TB (resistant to both isoniazid and rifampin and also resistant to a fluoroquinolone and at least one parenteral second-line antimycobacterial such as capreomycin, kanamycin, or amikacin), should be referred to or managed in consultation with experts in the treatment of TB as identified by local or state health departments or CDC.

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Treatment of latent tuberculosis infection is usually indicated, regardless of age, in patients who belong to one or more high-risk groups.

Rifampin may increase the metabolism of some drugs that also are metabolized by the liver including chloramphenicol, corticosteroids and anticoagulants.

Specifically, it is approved to treat tuberculosis and to get rid of bacteria known as Neisseria meningitides.

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Serious and sometimes fatal liver problems have occurred in patients taking crizotinib.

People should get most of their nutrients from food, advises the federal government's Dietary Guidelines for Americans.

Predisposing factors in hepatitis induced by isoniazid-rifampin treatment of tuberculosis.

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When rifampicin is taken with a meal, its peak blood concentration falls by 36%.

The upper parts of the lungs are most often affected.

ATS(American Thoracic Society) Hepatotoxicity of Antituberculosis Therapy Subcommittee.

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Although most individuals will require a larger reduction than what fiber monotherapy can provide, it is probably best when used in combination with other therapies.

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The chief risk of isoniazid (INH), the treatment of first choice for most patients with latent tuberculosis infection, is hepatotoxicity, but the drug can also cause anemia, gastrointestinal tract symptoms and peripheral neuropathy.

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Synergy for the antibiotic combinations could not be assessed because of the very low MIC values for tetracycline and doxycycline among these isolates.

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All patients with abnormalities should have follow-up, including laboratory testing, if necessary.

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Staphylococcus aureus infections, adjunctive therapy (off-label use): Oral, IV: 600 mg once daily or 300-450 mg every 12 hours with other antibiotics.

In the absence of evidence, they noted, clinicians continue to use empiric offlabel experimentation with various drugs, which raises safety and efficacy questions.

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Review necessity of infection control measures.

You should not use isoniazid and rifampin if you have active liver disease (including hepatitis or cirrhosis), or a history of liver problems caused by taking isoniazid.

These tests can help decrease the amount of time necessary for a presumptive diagnosis of tuberculosis to less than 24 hours.

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The MTBC result was then reported as positive (accompanied by a rifampin-susceptibility result), negative, equivocal, or inhibited.

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Additivity” or “indifference” is when the inhibitory activity of both of the agents is equal to the sum of the activity of the individual agents if they were used separately.

Adjunctive therapy with a corticosteroid is not recommended (weak, moderate).

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