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May be used for relief of ongoing ischemia or to control rapid ventricular response with atrial fibrillation after an acute MI when β-adrenergic blocking agents are ineffective or contraindicated, but only in patients in whom there is no evidence of heart failure, left-ventricular dysfunction, or AV block and only after weighing carefully the potential benefits versus risks, particularly negative inotropic effects and concerns about short-acting formulations of the drugs.

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