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Patients with encephalopathy consistent with herpes simplex encephalitis (HSE) whose cerebral spinal fluid (or brain biopsy sample) is positive for herpes simplex virus (HSV) deoxyribonucleic acid (DNA) by polymerase chain reaction (PCR).
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The morbidity and mortality of herpes zoster could be reduced if a safe and effective preventive treatment were available.
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Questionable benefit of prophylactic acyclovir in renal transplant recipients at high risk for cytomegalovirus disease.
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The same dose was also administered to 25 elderly subjects (mean age 76).
If the evaluation findings are abnormal, indicating the neonate already has neonatal HSV disease, the infant should be treated for 14 to 21 days with intravenous acyclovir on the basis of the extent of neonatal HSV disease (disseminated, CNS, or SEM) (AII); if the initial CSF PCR assay result is positive for HSV DNA, a repeat lumbar puncture should be obtained near the end of therapy (eg, on day 17 or 18 of an anticipated 21-day course of therapy), and intravenous acyclovir should be discontinued at 21 days if the repeat HSV PCR assay result is negative (AII).
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The tests that they do are: Immunofluorescence Assay, Polymerase Chain Reaction (PCR) and Virus Culture.
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Acyclovir to prevent reactivation of varicella zoster virus (herpes zoster) in multiple myeloma patients receiving bortezomib therapy.
Pharmacokinetic analysis was conducted by standard noncompartmental methods using WinNonlin software (Pharsight Corp.
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Oral acyclovir may abort recurrences if treatment is initiated immediately upon onset of symptoms; inhibits HSV-1 and HSV-2.
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About one third of acyclovir in the body is removed by dialysis during a 4-hour hemodialysis session.
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Analysis of late infections after human bone marrow transplantation: role of genotypic nonidentity between marrow donor and recipient and of nonspecific suppressor cells in patients with chronic graft-versus-host disease.
Any positive test result then requires further analysis to determine if the virus is HSV-1 or HSV-2.
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On the basis of current evidence, there is no rationale for prophylaxis against HSV, VZV, EBV or CMV during B-cell antibody treatment.
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The efficacy of valacyclovir tablets when initiated more than 72 hours after the onset of rash and the efficacy and safety of valacyclovir tablets for treatment of disseminated herpes zoster have not been established.
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