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Most participants commented on reductions in morbidity and mortality, but these positive responses were evident amongst both those caring for children who had received the placebo and those whose children had received the active drug.
L'association chloroquine-proguanil, sera ingérée, au cours d'un repas, en une prise ou par demi dose matin et soir en débutant 1 semaine avant le départ et jusqu'à 1 mois après le retour pour une personne pesant au moins 50 kg (pour une personne de moins de 50 kg, se référer au chapitre sur l'enfant voyageur).
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The number of patient in each group who developed a flare (according to the SELENA-SLEDAI composite criteria) during the study period.
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In addition, many children were not included in the trial because their family intended to travel, which was especially common amongst nomadic Peuhls in Mali and amongst migrant labourers in Burkina, who often travelled to Côte d'Ivoire.
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Savarino A, Boelaert JR, Cassone A, Majori G, Cauda R: Effects of chloroquine on viral infections: an old drug against today's diseases?
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When the trial team distributed LLINs at the start of the malaria season, many women arrived at the health centre in the middle of the night to ensure that they would not miss out, demonstrating the high value placed on this “gift” despite low levels of prior usage.
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To avoid this, the dose of chloroquine should not be taken within two to three hours of taking an antacid or kaolin.
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Six hundred twenty eight subjects who returned for at least one visit after day 0 and were included in the intention to treat (ITT) analysis.
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