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Is febuxostat safer than allopurinol? For most patients with gout and cardiovascular disease, febuxostat's mortality disadvantage makes allopurinol a safer bet. Febuxostat has been shown to be more effective than allopurinol in lowering uric acid levels, but the FDA required that a trial comparing the two drugs' cardiovascular safety be conducted.
Is Celebrex and ibuprofen the same thing? Celebrex (celecoxib) and ibuprofen are two nonsteroidal anti-inflammatory drugs (NSAIDs) that are used to treat pain from arthritis. Although both drugs are in the same class of medications, Celebrex and ibuprofen have some differences in how they work.

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