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I am a 45 year old female. It was a shock for me when the doctors diagnosed me with PBC about 3 years ago. Since that time I have had liver biopsies and blood tests for many times. Recently I started to notice that I am getting more tired and confused than before. My energy is gone. I asked my doctor to change the treatment and he put me on Ursodiol. I find it has helped me a lot. I do have some complications with my bowels but nothing too serious. I am pretty sure that it is Ursodiol that is to be in charge for all the improvement in my condition. Next week I am to undergo another series of tests, I believe they'll show I'm right.

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Global austerity, rapidly developing technology, ensuring high quality of care, pressures from an ageing population with more longterm conditions and political instability reflect the complexity of healthcare challenges.

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Although a significant period effect was observed, we conclude that a single dose of ursodiol has little effect on CsA absorption in liver transplant patients and that an interaction in the intestinal lumen between these two drugs is unlikely.

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